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GHK-Cu Side Effects and Safety Potential concerns include: Skin irritation, redness, or sensitivity (with topical use) Variable absorption depending on formulation, but newer research has demonstrated that adding in a transport vessel such as liposomes can help with topical absorption (12)

Despite these benefits, a 2023 meta-analysis found glutathione supplementation does not significantly increase erythrocyte or plasma levels

Some treatments also combine glutathione injections with Vitamin C or other antioxidants, enhancing results and offering additional skin-repairing benefits

doi: 10.1016/S0002-9343(98)00168-5 340 RimesKALievesleyKChalderT